The Panthers are going to be beastly in Madden 12.
The positives are obviously that it will be fun to play with a good team again.
The huge negative is that there are going to be a TON of people who jump on their bandwagon and use them in Madden to try and cheese for wins. It will give the sim player who uses the Panthers a bad reputation.
I cant wait for Madden 12 though!